How Does TACE Work to Treat Liver Tumors

How Does TACE Work to Treat Liver Tumors

Liver tumors can be challenging to treat, especially in cases where surgery isn’t a viable option. One of the advanced treatments available is Transarterial Chemoembolization (TACE). This minimally invasive procedure combines targeted chemotherapy delivery with embolization, which blocks the tumor’s blood supply, making it an effective treatment for liver tumors. Let’s dive deeper into how TACE works to treat liver tumors and why it’s gaining popularity among specialists and patients alike.

What is TACE?

Transarterial Chemoembolization (TACE) is a medical procedure used to treat certain types of liver cancer. It works by delivering chemotherapy drugs directly to the tumor through the blood vessels while simultaneously blocking the blood supply to the tumor. This combined approach helps target the cancer effectively while minimizing damage to healthy tissues nearby.

TACE is typically used for patients with hepatocellular carcinoma, the most common form of liver cancer, or those with liver cancer that has spread from other parts of the body. It is especially useful for patients who cannot undergo surgery or liver transplantation, providing a less invasive alternative for managing their condition.

How Does TACE Work

To understand how TACE works, it is essential to break down its step-by-step process:

1. Catheter Insertion

The procedure starts with a tiny incision in the groin, through which a catheter is inserted into the femoral artery. Using advanced imaging guidance, the catheter is carefully navigated to the hepatic artery, the main blood vessel supplying the liver tumor.

2. Localized Chemotherapy Delivery

Once the catheter reaches the targeted area, chemotherapy drugs are injected directly into the artery supplying the tumor. This ensures a highly concentrated dose of medication is delivered precisely to the tumor site.

3. Embolization

After chemotherapy delivery, embolic agents (such as tiny beads or particles) are released through the catheter. These agents block the blood supply to the tumor, depriving it of the oxygen and nutrients it needs to grow.

4. Selective Targeting

TACE leverages the liver’s unique dual blood supply system. While the tumour primarily depends on the hepatic artery, healthy liver tissues receive blood from the portal vein. This enables TACE to target only the tumour, preserving the functionality of the surrounding liver tissue.

Who is a Candidate for TACE?

Candidates for Transarterial Chemoembolization (TACE) generally meet the following criteria:

  • Unresectable Liver Cancer: Tumors that are too large, numerous, or inoperable areas.
  • Suitable Liver Function: Child-Pugh A or B liver function score indicates the liver can handle the procedure.
  • Localized Cancer: Cancer confined to the liver, with minimal spread.
  • Good Performance Status: Patients must be physically able to tolerate the procedure.
  • BCLC Stage B: Most candidates are in this stage of liver cancer.
  • Tumour Vascularity: TACE is effective on tumours with a good blood supply.

Benefits of TACE in Liver Tumor Treatment

TACE has become one of the most sought-after treatments for liver tumors due to its precision and effectiveness. Here are some key benefits:

1. Minimally Invasive

As a minimally invasive procedure, TACE requires only a small incision and has a lower risk of complications than traditional surgeries. Patients experience faster recovery times and less discomfort.

2. Targeted Treatment

By delivering chemotherapy directly to the tumor, TACE minimizes exposure to the rest of the body. This reduces systemic side effects while maximizing the impact on the tumor.

3. Tumor Shrinkage and Growth Control

The combination of chemotherapy and embolization helps shrink tumors and control their growth. This improves the patient’s prognosis and enhances their quality of life.

4. Tailored Approach

TACE is highly customized based on the size, location, and type of tumor, making it a versatile treatment option for different patients.

About Dr. Nikhil Bansal – A Leading TACE Specialist in Jaipur

Dr. Nikhil Bansal is one of Jaipur’s most reliable TACE specialists, with over eight years of experience in interventional radiology and endovascular procedures. He works on minimal invasion techniques like Trans-arterial Chemo-embolization (TACE) for effectively treating liver tumors. He has been focused on precision and individualized care; he always strives to make the treatment plan suited to their medical needs.

After extensive training in interventional radiology, he has acquired experience in a broad number of complex conditions with the use of advanced techniques in imaging and procedures for treatment. His patient-centric approach and commitment to minimally invasive solutions led him to head the group dedicated to TACE and liver tumor treatment.